Positional specificity of cyclopropane ring formation from cis-octadecenoic acid isomers in Escherichia coli

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Positional specificity of cyclopropane ring formation from cis-octadecenoic acid isomers in Escherichia coli.

An unsaturated fatty acid auxotroph of Escherichia coli was grown with a series of cis-octadecenoate isomers in which the location of the double bond varied from positions 3 to 17. Each of these fatty acid isomers was incorporated into the cellular lipids, but cyclopropane derivatives were formed to at least a 3-fold greater extent from the cis-9 and cis-11 isomers than from any other positiona...

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Polymorphism in Single-Acid Triglycerides of Positional and Geometric Isomers of Octadecenoic Acid

The polymorphism of 25 glycerol trioctadecenoates with double bonds ranging from ~4-~ I 7 was investigated by differential scanning calorimetry. Triglycerides with cis bonds in odd positions ~7-~13 exhibited three intermediate melting (13'-) forms, but those with cis bonds in even positions, except cis ~4, lacked 13'-forms. Among the trans compounds, only ~ 11, 13, and 14 showed 13'-forms. The ...

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Coexpressing Escherichia coli cyclopropane synthase with Sterculia foetida Lysophosphatidic acid acyltransferase enhances cyclopropane fatty acid accumulation.

Cyclopropane fatty acids (CPAs) are desirable as renewable chemical feedstocks for the production of paints, plastics, and lubricants. Toward our goal of creating a CPA-accumulating crop, we expressed nine higher plant cyclopropane synthase (CPS) enzymes in the seeds of fad2fae1 Arabidopsis (Arabidopsis thaliana) and observed accumulation of less than 1% CPA. Surprisingly, expression of the Esc...

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In vivo distribution and turnover of trans- and cis-10-octadecenoic acid isomers in human plasma lipids.

Triacylglycerols containing deuterium-labeled trans-10- and cis-10-octadecenoic acid (10t-18:1, 10c-18:1) plus the triacylglycerol of deuterated cis-9-octadecenoic acid (9c-18:1) were fed as a mixture to two young, adult male subjects. Analysis by mass spectroscopy of the labeled fats in blood samples collected periodically for 48 h allowed the uptake, distribution and turnover of both 10-octad...

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Coexpressing Escherichia coli Cyclopropane Synthase with Sterculia foetida Lysophosphatidic Acid Acyltransferase Enhances Cyclopropane Fatty Acid Accumulation1[W][OPEN]

Cyclopropane fatty acids (CPAs) are desirable as renewable chemical feedstocks for the production of paints, plastics, and lubricants. Toward our goal of creating a CPA-accumulating crop, we expressed nine higher plant cyclopropane synthase (CPS) enzymes in the seeds of fad2fae1 Arabidopsis (Arabidopsis thaliana) and observed accumulation of less than 1% CPA. Surprisingly, expression of the Esc...

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ژورنال

عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

سال: 1976

ISSN: 0005-2760

DOI: 10.1016/0005-2760(76)90146-6